FACULTY OF PHARMACY




                                             Course Module
        Subject: PHARMACOGNOSY-IV                                      Subject Code: PHM 3.5.4
        Class: B.Pharmacy Semester -V                                  Total Lectures: 45
        Theory: 4 hr/week                                              Practical: 4 hr/week
        Lecturer: Mr. Neeraj Choudhary                                 Phone: 09417590856
        E-mail: Neeraj_pharm2008@rediffmail.com

       Objectives:
          The major objective of this subject to study the modern and advancement in Herbal Drug Resarch. The
         knowledge and deep understanding of Pharmacognosy helps a student to apply the knowledge in herbal
         pharmaceutical industry.

Teaching Methods:
     Lectures, Tests, Assignments, Presentations and activities




Module Outline:

        Lectures                                            Topics
            1.     Biological sources, Prepration ,identifications tests and uses of the following enzymes-
                   Diastase, papain, pepsin, trypsin, pancreartin
            2.                             -do-
            3.     Plant bitters and sweeteners.
            4.                             -do-
            5.     Role of medicinal plant and aromatic plants in national economy.
            6.                             -do-
            7.     General biosynthetic pathways of natural products like alkaloids, glycosides, terpenoids,
                   lignans,quassinoids, carotenoids and flavonoids.
            8.                             -do-
            9.                             -do-
           10.                             -do-
           11.                             -do-
           12.     Systematic study of source, cultivation, collection, processing, commercial varieties,
                   chemical constituents,substitutes, adulterants, uses, and specific chemical tests of
                   following alkaloid containing drugs :
           13.     Pyridine - piperidine: Tobacco, areca and lobelia
           14.                             -do-
           15.                             -do-
           16.     Tropane: Belladonna, hyoscyamus, datura, duboisia, coca and withania.
           17.                             -do-
           18.                             -do-
           19.                             -do-
           20.     Quinoline and isoquinoline: cinchona, ipecac, opium
           21.                             -do-
           22.                             -do-
           23.     Indole: Ergot, rauwolfia, catharanthus, nux-vomica and physostigma.
24.                            -do-
      25.                            -do-
      26.                            -do-
      27.     Imidazole: Pilocarpus
      28.     Steroidal: Veratrum and kurchi
      29.     Alkaloidal amine: Ephedra and colchicum
      30.     Glycoalkaloid: Solanum
      31.     Purines: Coffee, tea and cola
      32.                           -do-
      33.     Introduction, classification and study of different chromatographic methods and their
              applications inevaluation of herbal drugs.
      34.                             -do-
      35.                             -do-




Modes of Assessment:

            Modes of Assessment                              Score
Assignment                                                     10
Presentation                                                   10
Mid semester exam                                              40
 st
1 Hourly test                                                  20
2nd Hourly test                                                20
Total marks                                                   100




Books Recommended
1. Trease, G. E. and Evans, W.C. Pharmacognosy, Published by Elsevier, a Division of Reed Elsevier India
Pvt. Ltd., New Delhi.
2. Kokate, C.K., Purohit, A.P. and Gokhale, S.B Pharmacognosy, Nirali Prakashan, Pune.
3. Handa, S.S and Kapoor, V.K. Textbook of Pharmacognosy, Vallabh Prashan, New Delhi.
4. Medicinal Plants of India. ICMR, New Delhi.
5. Wallis, T.E. Textbook of Pharmacognosy, Fifth Edition, CBS Publishers and Distributors, New Delhi.
6. Tyler, V.C., Brady, L.R. and Robers, J.E. Pharmacognosy. Lea & Febiger, Philadelphia.


                                Topics for Presentation & Assignments
        Role of medicinal and aromatic plants in                 piperidine: Tobacco
                    national economy.
       Tropane: Belladonna, hyoscyamus, datura,              Plant bitters and sweeteners.
               duboisia, coca and withania
                  Imidazole: Pilocarpus                        Glycoalkaloid: Solanum
              Purines: Coffee, tea and cola.                    Imidazole: Pilocarpus
      General biosynthetic pathways of natural     Introduction, classification and study of
      products like alkaloids, glycosides,         different chromatographic methods and their
      terpenoids, lignans,quassinoids, carotenoids applications inevaluation of herbal drugs.
      and flavonoids.
      Imidazole: Pilocarpus                                Steroidal: Veratrum and kurchi
         Quinoline and isoquinoline: cinchona,        Tropane: Belladonna, hyoscyamus, datura,
                      ipecac, opium                          duboisia, coca and withania.
Pharmacognosy Practical

          S.No.                              Name of experiment
             1    General introduction to Alkaloids
             2    To study the powder microscopy of the Ashwagandha.
             3    To study the powder microscopy of the Rauwolfia.
             4    To study the powder microscopy of the Datura leaves.
             5    To study the powder microscopy of the Nux-vomica.
             6    To study the powder microscopy of the vinca.
             7    To study the powder morphology of the vinca
             8    To study the powder microscopy of the Kurchi.
             9    To study the powder microscopy of the ephedra.
            10    To study the powder microscopy of the punarnava.
            11    To prepare TLC plate.
            12    To separate the active constituents from Nux-vomica by TLC
            13    Study organoleptic drugs.
            14    T.S of clove
            15    T.S of coriander.
            16    T.S of Datura.
           17..   T.S of vinca


Instruction for students:
    1. Assignment must neatly presented
    2. Late submission is not permissible and will attract minimum awards.
    3. Presentation is compulsory
    4. Each group is assigned different subject for the presentation day.
    5. The presentation day attendance is equivalent to 4 lectures.
    6. The synopsis must be submitted one week before the presentation.
    7. 75% attendance is mandatory, below this percentage; student will not be allowed to appear in the
         examination.
    8. The student will record the details of practicals in the practical note book and get it checked every
         time from the instructor after the experiment has been completed.

Pharmacognosy 5th sem

  • 1.
    FACULTY OF PHARMACY Course Module Subject: PHARMACOGNOSY-IV Subject Code: PHM 3.5.4 Class: B.Pharmacy Semester -V Total Lectures: 45 Theory: 4 hr/week Practical: 4 hr/week Lecturer: Mr. Neeraj Choudhary Phone: 09417590856 E-mail: Neeraj_pharm2008@rediffmail.com Objectives: The major objective of this subject to study the modern and advancement in Herbal Drug Resarch. The knowledge and deep understanding of Pharmacognosy helps a student to apply the knowledge in herbal pharmaceutical industry. Teaching Methods: Lectures, Tests, Assignments, Presentations and activities Module Outline: Lectures Topics 1. Biological sources, Prepration ,identifications tests and uses of the following enzymes- Diastase, papain, pepsin, trypsin, pancreartin 2. -do- 3. Plant bitters and sweeteners. 4. -do- 5. Role of medicinal plant and aromatic plants in national economy. 6. -do- 7. General biosynthetic pathways of natural products like alkaloids, glycosides, terpenoids, lignans,quassinoids, carotenoids and flavonoids. 8. -do- 9. -do- 10. -do- 11. -do- 12. Systematic study of source, cultivation, collection, processing, commercial varieties, chemical constituents,substitutes, adulterants, uses, and specific chemical tests of following alkaloid containing drugs : 13. Pyridine - piperidine: Tobacco, areca and lobelia 14. -do- 15. -do- 16. Tropane: Belladonna, hyoscyamus, datura, duboisia, coca and withania. 17. -do- 18. -do- 19. -do- 20. Quinoline and isoquinoline: cinchona, ipecac, opium 21. -do- 22. -do- 23. Indole: Ergot, rauwolfia, catharanthus, nux-vomica and physostigma.
  • 2.
    24. -do- 25. -do- 26. -do- 27. Imidazole: Pilocarpus 28. Steroidal: Veratrum and kurchi 29. Alkaloidal amine: Ephedra and colchicum 30. Glycoalkaloid: Solanum 31. Purines: Coffee, tea and cola 32. -do- 33. Introduction, classification and study of different chromatographic methods and their applications inevaluation of herbal drugs. 34. -do- 35. -do- Modes of Assessment: Modes of Assessment Score Assignment 10 Presentation 10 Mid semester exam 40 st 1 Hourly test 20 2nd Hourly test 20 Total marks 100 Books Recommended 1. Trease, G. E. and Evans, W.C. Pharmacognosy, Published by Elsevier, a Division of Reed Elsevier India Pvt. Ltd., New Delhi. 2. Kokate, C.K., Purohit, A.P. and Gokhale, S.B Pharmacognosy, Nirali Prakashan, Pune. 3. Handa, S.S and Kapoor, V.K. Textbook of Pharmacognosy, Vallabh Prashan, New Delhi. 4. Medicinal Plants of India. ICMR, New Delhi. 5. Wallis, T.E. Textbook of Pharmacognosy, Fifth Edition, CBS Publishers and Distributors, New Delhi. 6. Tyler, V.C., Brady, L.R. and Robers, J.E. Pharmacognosy. Lea & Febiger, Philadelphia. Topics for Presentation & Assignments Role of medicinal and aromatic plants in piperidine: Tobacco national economy. Tropane: Belladonna, hyoscyamus, datura, Plant bitters and sweeteners. duboisia, coca and withania Imidazole: Pilocarpus Glycoalkaloid: Solanum Purines: Coffee, tea and cola. Imidazole: Pilocarpus General biosynthetic pathways of natural Introduction, classification and study of products like alkaloids, glycosides, different chromatographic methods and their terpenoids, lignans,quassinoids, carotenoids applications inevaluation of herbal drugs. and flavonoids. Imidazole: Pilocarpus Steroidal: Veratrum and kurchi Quinoline and isoquinoline: cinchona, Tropane: Belladonna, hyoscyamus, datura, ipecac, opium duboisia, coca and withania.
  • 3.
    Pharmacognosy Practical S.No. Name of experiment 1 General introduction to Alkaloids 2 To study the powder microscopy of the Ashwagandha. 3 To study the powder microscopy of the Rauwolfia. 4 To study the powder microscopy of the Datura leaves. 5 To study the powder microscopy of the Nux-vomica. 6 To study the powder microscopy of the vinca. 7 To study the powder morphology of the vinca 8 To study the powder microscopy of the Kurchi. 9 To study the powder microscopy of the ephedra. 10 To study the powder microscopy of the punarnava. 11 To prepare TLC plate. 12 To separate the active constituents from Nux-vomica by TLC 13 Study organoleptic drugs. 14 T.S of clove 15 T.S of coriander. 16 T.S of Datura. 17.. T.S of vinca Instruction for students: 1. Assignment must neatly presented 2. Late submission is not permissible and will attract minimum awards. 3. Presentation is compulsory 4. Each group is assigned different subject for the presentation day. 5. The presentation day attendance is equivalent to 4 lectures. 6. The synopsis must be submitted one week before the presentation. 7. 75% attendance is mandatory, below this percentage; student will not be allowed to appear in the examination. 8. The student will record the details of practicals in the practical note book and get it checked every time from the instructor after the experiment has been completed.